Cowboys vs. Giants odds, spread, line: Monday Night Football picks, predictions by NFL model on 139-102 roll

The Dallas Cowboys will try to continue their dominance of the series when they visit the upstart New York Giants on Monday Night Football. Dallas has won nine of the past 10 meetings, but comes in without quarterback Dak Prescott to face a New York squad that is 2-0. The Giants edged the Carolina Panthers 19-16 last Sunday to get halfway to their 2021 win total. They went 4-13 last season, but they have been finding a way to win under new coach Brian Daboll. The Cowboys needed a last-second field goal to upset the Cincinnati Bengals last Sunday with Cooper Rush leading the Dallas offense.

Kickoff is set for 8:15 p.m. ET at MetLife Stadium in East Rutherford, N.J. Caesars Sportsbook lists New York as a 1-point favorite in its latest Cowboys vs. Giants odds, and the over/under for total points scored is 39.5. Before you lock in any Giants vs. Cowboys picks, you have to check out the NFL predictions and betting advice from the SportsLine Projection Model.

The model, which simulates every NFL game 10,000 times, is up more than $7,000 for $100 players on top-rated NFL picks since its inception. The model enters Week 3 of the 2022 NFL season on an incredible 139-102 run on top-rated NFL picks that dates back to the 2017 season.

The model also ranked in the top 10 on NFLPickWatch four of the past six years on straight-up NFL picks and beat more than 94% of CBS Sports Football Pick’em players four times during that span. Anyone who has followed it is way up.

Now, the model has broken down Monday’s Cowboys vs. Giants matchup and just locked in its picks and MNF predictions. You can head to SportsLine now to see the model’s picks. Here are the NFL odds and betting lines for Giants vs. Cowboys:  

Featured Game | New York Giants vs. Dallas Cowboys

Why the Giants can cover

Running back Saquon Barkley has topped 70 rushing yards in consecutive games for the first time since 2019. That approach could work against Dallas, which is sixth against the pass but 19th against the run (120.5 yards per game). Quarterback Daniel Jones has just 356 passing yards,but is completing almost 71 percent of his throws.

The favorite is 7-3 against the spread in the past 10 meetings. While the Giants have won just one of the past 10 meetings, that one victory was a game Prescott missed. The defense will get after Cooper Rush, who is making his third start in a hostile environment. The Giants hurry the quarterback on 14 percent of dropbacks (fifth in NFL), and Cowboys QBs were knocked down on 11 percent of dropbacks in 2021 (fourth-most).

Why the Cowboys can cover

Dallas is 8-2 ATS in the past 10 meetings, covering in both in 2021, and has won nine of the 10 outright. Cooper Rush had a strong 2022 debut in place of Prescott, completing 19 of 31 passes for 235 yards, a touchdown and no interceptions. Tony Pollard had 98 total yards and a score, and young star CeeDee Lamb had seven catches for 75 yards. Rush showed chemistry with Noah Brown, who had five catches for a team-high 91 yards and a score against the Bengals. The Cowboys also still have Ezekiel Elliott, who has almost 7,500 career rushing yards.

The defense is allowing 300 yards per game (sixth in NFL) on the strength of a pass defense yielding 180 (also sixth). The Cowboys are second in the NFL with eight sacks and allow just 4.7 yards per play (sixth). They have just one takeaway, but they led the NFL with 34 in 2021 and had a plus-14 turnover margin (T-1). Giants quarterback Daniel Jones has been sacked eight times and has one interception after going down 22 times and throwing seven picks in 11 games last season.

How to make Cowboys vs. Giants picks

The model has broken down Monday night’s Giants vs. Cowboys matchup from all angles. It is leaning Over on the point total, suggesting both teams will find success in the running game. The model also says one side has all the value. You can only get the model’s MNF picks at SportsLine.

So who wins Giants vs. Cowboys on Monday Night Football? And which side of the spread has all the value? Visit SportsLine right now to find out which side of the Giants vs. Cowboys spread you should be all over Monday, all from the model on a 139-102 roll on its top-rated NFL picks, and find out.