An 18th-century villa is again a stage for history.

A storied villa on the shores of Lake Geneva is sometimes described as having “a certain sense of mystery about it,” but there was little mystery this week about why the mansion and the park surrounding it were closed off.

Visitors were coming.

The Villa la Grange, an 18th-century manor house at the center of Parc la Grange, is the site of the meeting on Wednesday between President Biden and President Vladimir V. Putin.

Set in one of Geneva’s largest and most popular parks, the site is known not just for its lush gardens, but also for its role as a setting for important moments in the struggle between war and peace.

In 1825, the villa’s library — home to over 15,000 works and the only room to retain the villa’s original decorative features — hosted dignitaries of a European gathering that aimed to help Greeks fighting for independence.

Designed by the architect Jean-Louis Bovet and completed in 1773, the villa was owned by the Lullin family and primarily used as a summer residence before it was bought by a merchant, François Favre, in 1800.

It cemented its place in history in 1864, when is was the site of a closing gala for officials who signed the original 1864 Geneva Convention, presided over by Henri Dunant, a founder of the International Red Cross. An attempt to ameliorate the ravages of war on both soldiers and civilians, it set minimum protections for people who are victims of armed conflict.

After World War II, a new draft of the conventions was signed in an attempt to address gaps in international humanitarian law that the conflict had exposed.

In 1969, Pope Paul VI, who traveled to the park to celebrate Mass for a congregation of tens of thousands, pointed to the villa’s history as he spoke about the risk of nuclear conflagration.

He spoke about the opposing forces of love and hate and called for “generous peacemakers.”