November 25, 2024

Indianapolis Colts at Jacksonville Jaguars odds, picks and predictions

Colts -3 #Colts-3

The Indianapolis Colts (0-0-1) and Jacksonville Jaguars (0-1) continue their AFC South rivalry Sunday at TIAA Bank Field in Jacksonville, Fla. Kickoff is set for 1 p.m. ET (CBS). Below, we analyze Tipico Sportsbook‘s lines around the Colts vs. Jaguars odds, and make our expert NFL picks and predictions.

The Colts tied the Houston Texans 20-20 in Week 1 after both squads failed to score in overtime. QB Matt Ryan had a solid day with 352 yards passing, 1 TD and 1 INT. He found WR Michael Pittman Jr. for 121 of those yards on 9 receptions. RB Jonathan Taylor continued to show why he’s the NFL’s top back, earning 161 yards and a TD on 31 carries.

The Jaguars lost on the road last week 28-22 to the Washington Commanders. Jacksonville led 22-14 in the 4th quarter, but allowed 14 unanswered points in the final 10 minutes. Second-year QB Trevor Lawrence passed for 275 yards and 1 TD and 1 INT. His favorite target was newly-acquired WR Christian Kirk, who had 6 receptions for 117 yards.

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Colts at Jaguars odds

Provided by Tipico Sportsbook; access USA TODAY Sports Scores and Sports Betting Odds hub for a full list. Lines last updated at 1:26 a.m. ET.

  • Money line (ML): Colts -165 (bet $165 to win $100) | Jaguars +140 (bet $100 to win $140)
  • Against the spread (ATS): Colts -3.5 (+102) | Jaguars +3.5 (-125)
  • Over/Under (O/U): 44.5 (O: -112 | U: -108)
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    Colts at Jaguars key injuries

    Colts

  • WR Alec Pierce (concussion) out
  • WR Michael Pittman Jr. (quad) out
  • DT DeForest Buckner (hip) questionable
  • CB Kenny Moore II (hip) questionable
  • Jaguars

    Colts at Jaguars picks and predictions Prediction

    Jaguars 24, Colts 20

    Money line

    If you’re ever going to play Jacksonville as an underdog, right now may be the perfect time to do it. The Colts are already banged up just 2 weeks into the season, missing 2 of their top WRs in Pittman and Pierce. They’ll rely on the running game with Taylor, but that 1-dimensional offensive approach may not be enough to take out the Jags on the road.

    I like the JAGUARS +140.

    Against the spread

    If you’re not quite sold on taking the Jags straight up, that’s okay. Play the JAGUARS +3.5 (-125). Both matchups from each squad last week suggest they’ll play teams close, plus this is a divisional matchup where each team will throw out its best. Recent history shows the Jags should cover as well — they’re 4-0 ATS vs. the Colts in their last 4 matchups.

    Over/Under

    I try to avoid over/unders on total points at the beginning of the season until teams and trends are more established. That said, if you’re dying to put something down on this, I’d lightly lean toward UNDER 44.5 (-108) for the sole fact that neither offense appears to be that good (yet). The Colts will run the ball more which means draining more clock, while the Jaguars have yet to do anything to show that their offense can consistently put up big points.

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