49ers vs. Giants score: Deebo Samuel monster night powers San Francisco to win, 3-0 start to season

The Giants pulled off a miracle against the Cardinals in Week 2, overcoming a 21-point second-half lead to avoid a winless start to the season. They were unable to muster that same magic on Thursday night, however, as New York couldn’t rally and fell 30-12 to the 49ers.

There was one main difference between the 49ers and Giants, and it was a glaring one. While the Saquon Barkley-less Giants are devoid of playmakers, the 49ers have several, including former All-Pro wideout Deebo Samuel, who caught six passes for 129 yards on Thursday night that included the game-clinching touchdown. 

Samuel’s brilliance was flanked by the 49ers’ other offensive stars. Christian McCaffrey tallied 119 total yards while tying Jerry Rice’s franchise record by scoring a touchdown in 12 consecutive games. George Kittle caught seven passes for 90 yards. Second-year quarterback Brock Purdy threw for 310 yards and two touchdowns while improving to 8-0 as the 49ers’ starting quarterback during the regular season. 

The 49ers’ offense was good, but their defense was just as impressive on Thursday night. Led by reigning Defensive Player of the Year Nick Bosa, the 49ers’ defense held the Giants’ offense to just 10 first downs and 150 total yards. 

We’ll have a deeper breakdown of the 49ers’ win shortly, but in the meantime, check out our live blog below to relive the action in real time.